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Salicylic acid is contraindicated for individuals taking which medication?

  1. Minocycline

  2. Isotretinoin

  3. Aspirin

  4. Hydrocortisone

The correct answer is: Isotretinoin

Salicylic acid is contraindicated for individuals taking isotretinoin due to the potential for increased skin sensitivity and irritation. Isotretinoin is a powerful retinoid used primarily for severe acne, and it significantly alters the skin's barrier function. When combined with salicylic acid, which is an exfoliant and can cause skin peeling, there is an elevated risk of excessive dryness, irritation, and even inflammatory responses. Professionals recommend avoiding the use of salicylic acid and similar products while a person is on isotretinoin to ensure safe and effective care of the skin. The other medications listed, such as minocycline, aspirin, and hydrocortisone, do not have the same level of contraindication with salicylic acid. While they may have their own unique considerations, they do not pose the same significant risk of irritation when used together as salicylic acid does with isotretinoin.