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What effect does isotretinoin have on the skin?

  1. Increases oil production

  2. Reduces acne

  3. Increases sensitivity

  4. Enhances pigmentation

The correct answer is: Reduces acne

Isotretinoin is a powerful medication primarily used to treat severe acne. Its main effect on the skin is reducing acne by targeting the underlying causes. Isotretinoin works by decreasing the size and output of sebaceous (oil) glands, leading to a significant reduction in oil production, which is a major factor in acne development. Additionally, it also helps to normalize skin cell turnover and reduce inflammation, both of which contribute to the effectiveness of the treatment in managing and clearing acne lesions. This medication is particularly beneficial for individuals with cystic or nodular acne, which is resistant to other forms of treatment. By drastically diminishing the formation of acne, isotretinoin allows the skin to heal and improves its overall appearance. The other choices reflect effects that do not align with isotretinoin’s primary purpose or clinical outcomes. For instance, while increased sensitivity can occur in some individuals taking isotretinoin due to its impact on the skin's barrier, it is not the primary therapeutic goal. The medication does not enhance pigmentation; rather, it can sometimes lead to a lighter skin tone. Overall, isotretinoin's primary and most significant effect is its ability to reduce acne effectively.